GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10461617 | 1 | rs252898 | chr5:56188931 | C5orf35 | chr5:56205103-56213010:+ | 0.75 | 11.57 | 9.06E-27 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252902 | chr5:56116085 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.35 | 6.18E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252904 | chr5:56118733 | C5orf35 | chr5:56205103-56213010:+ | 0.72 | 11.24 | 1.58E-25 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252909 | chr5:56121131 | C5orf35 | chr5:56205103-56213010:+ | 0.73 | 10.99 | 1.34E-24 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252910 | chr5:56192983 | C5orf35 | chr5:56205103-56213010:+ | 0.78 | 11.43 | 3.13E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252915 | chr5:56121754 | C5orf35 | chr5:56205103-56213010:+ | -0.75 | -11.37 | 5.13E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252916 | chr5:56121788 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.59 | 7.71E-27 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252919 | chr5:56124111 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.46 | 2.48E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252921 | chr5:56137787 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.74 | 2.13E-27 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs252922 | chr5:56136343 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.56 | 9.96E-27 | Type 2 diabetes |
| BLCA | cis | rs2243480 | 1 | rs2533288 | chr7:66056711 | CCT6P1 | chr7:65216092-65228661:+ | 0.35 | 4.68 | 4.02E-6 | Diabetic kidney disease |
| BLCA | cis | rs7849270 | 1 | rs2541164 | chr9:131876908 | CRAT | chr9:131857075-131873070:- | 0.3 | 5.24 | 2.61E-7 | Blood metabolite ratios |
| BLCA | cis | rs10461617 | 1 | rs2548664 | chr5:56133555 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.34 | 6.98E-26 | Type 2 diabetes |
| BLCA | cis | rs10461617 | 1 | rs2548665 | chr5:56131805 | C5orf35 | chr5:56205103-56213010:+ | 0.74 | 11.34 | 6.98E-26 | Type 2 diabetes |
| BLCA | cis | rs891378 | 1 | rs2564978 | chr1:207494416 | CD55 | chr1:207494817-207534309:+ | 0.23 | 3.94 | 9.81E-5 | Spherical equivalent (joint main effects and education interaction) |